Table 1.
Animal characteristics at the end of experiment, according to study group (n = 5–6 per group)
| Characteristic | Control | Diabetes mellitus | Diabetes mellitus + trimetazidine |
|---|---|---|---|
| Body weight (g) | 434.17 ± 8.60 | 470.17 ± 27.874 | 433.67 ± 7.893 |
| Heart weight (mg) | 1096.00 ± 35.86 | 1463.33 ± 37.83* | 1293.86 ± 47.94** |
| Water intake (mL/day) | 28.20 ± 3.455 | 153.83 ± 10.329* | 147.00 ± 10.440 |
| Food intake (g/day) | 14.44 ± 0.423 | 29.95 ± 1.090* | 29.00 ± 1.163 |
| Urine volume (mL/day) | 22.60 ± 2.502 | 126.33 ± 7.766* | 129.00 ± 10.416 |
| Systolic blood pressure (mm Hg) | 123.40 ± 4.490 | 120.67 ± 3.964 | 116.40 ± 5.609 |
| Diastolic blood pressure (mm Hg) | 89.00 ± 4.025 | 77.17 ± 4.888 | 84.20 ± 2.354 |
| Mean pressure (mm Hg) | 103.80 ± 5.229 | 90.33 ± 5.245 | 94.80 ± 3.089 |
| Heart rate (bpm) | 454.20 ± 15.714 | 491.67 ± 13.601 | 343.20 ± 14.235** |
Values are mean ± SEM. bpm, beats per minute
*p < 0.05 compared with control group; and **p < 0.05 compared with diabetes group