Figure 2.

Mean lesion number and gastric blood flow (GBF) in gastric mucosa pretreated with vehicle (saline; i.g.; yellow pattern), RuCl₃ (1 mg/kg i.g.; mosaic patttern), carbon monoxide releasing molecule 2 (CORM-2, 1 mg/kg i.g.; brick pattern) and zinc protoporphyrin IX (ZnPP, 10 mg/kg, intraperitoneally (i.p.); brick pattern) administered alone or in combination with CORM-2 and compromised 30 min later by water immersion and restraint stress (WRS). Results are mean ± S.D. of 6–8 animals for each experimental group. Asterisk indicates significant change (p < 0.05) as compared with vehicle (saline). Cross indicates significant change (p < 0.05) as compared with the group treated with CORM-2 (1 mg/kg i.g.) alone.