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Mean lesion number and gastric blood flow (GBF) in gastric mucosa pretreated i.g. with vehicle (saline) or hemin administered in increasing doses ranging from 1 up to 10 mg/kg i.g. and exposed 30 min later to water immersion and restraint stress (WRS). Results are mean ± S.D. of 4–6 animals for each experimental group. Asterisk indicates significant change (p < 0.05) as compared with vehicle (saline).
