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. 2016 Mar 30;17(4):457. doi: 10.3390/ijms17040457

Table 3.

Genotype frequencies of rs17810546 in CD and control groups and genotype effects in the meta-analysis.

Author and Year CD Group Control Group G vs. A AG vs. AA GG vs. AA HWE p Value
AA AG GG AA AG GG OR 95% CI OR 95% CI OR 95% CI
Van Heel 2007 UK [18] 546 211 20 1094 307 22 1.37 1.15–1.63 1.38 1.12–1.69 1.82 0.99–3.37 0.930
Hunt 2008 UK [6] 524 179 15 1190 346 25 1.17 0.98–1.40 1.17 0.95–1.45 1.36 0.71–2.61 0.979
Hunt 2008 Ireland [6] 277 125 14 724 216 16 1.51 1.21–1.88 1.51 1.17–1.96 2.29 1.10–4.75 0.980
Hunt 2008 Netherlands [6] 349 144 15 681 193 14 1.45 1.17–1.80 1.46 1.13–1.87 2.09 1.00–4.38 0.938
Romanos 2008 Italy [16] 427 105 6 521 75 3 1.68 1.25–2.26 1.71 1.24–2.36 2.44 0.61–9.81 0.865
Coenen 2009 Netherlands [14] 548 224 23 1303 355 24 1.50 1.27–1.78 1.50 1.23–1.82 2.28 1.28–4.07 0.974
Dubois 2010 UK1 [15] 515 202 20 2019 540 36 1.47 1.25–1.85 1.47 1.21–1.77 2.18 1.25–3.79 0.987
Dubois 2010 UK2 [15] 1339 469 41 3814 1050 72 1.27 1.14–1.42 1.27 1.12–1.44 1.62 1.10–2.39 0.977
Dubois 2010 Finland [15] 487 148 11 1478 332 19 1.35 1.11–1.63 1.35 1.09–1.68 1.76 0.83–3.72 0.941
Dubois 2010 Netherlands [15] 555 226 23 658 176 12 1.52 1.25–1.73 1.52 1.21–1.91 2.27 1.12–4.61 0.952
Dubois 2010 Italy [15] 392 99 6 473 68 2 1.77 1.30–2.41 1.76 1.25–2.46 3.62 0.73–18.04 0.788
Dubois 2010 USA [15] 720 234 19 432 116 8 1.21 0.97–1.51 1.21 0.94–1.56 1.42 0.62–3.28 0.946
Dubois 2010 Hungary [15] 674 265 26 839 214 14 1.54 1.28–1.84 1.54 1.25–2.45 2.31 1.20–4.46 0.932
Dubois 2010 Ireland [15] 398 179 20 1094 336 26 1.46 1.22–1.75 1.46 1.18–1.81 2.11 1.17–3.83 0.972
Dubois 2010 Poland [15] 390 158 16 538 165 13 1.32 1.06–1.64 1.32 1.02–1.70 1.70 0.81–3.57 0.932
Dubois 2010 Spain [15] 439 105 6 355 74 4 1.14 0.85–1.53 1.15 0.83–1.59 1.21 0.34–4.33 0.947
Dubois 2010 Italy [15] 825 175 9 683 116 5 1.24 0.98–1.57 1.25 0.97–1.61 1.49 0.50–4.47 0.975
Dubois 2010 Finland [15] 200 55 4 514 131 8 1.09 0.80–1.50 1.08 0.76–1.54 1.28 0.38–4.31 0.914
Sperandeo 2011 Italy [17] 526 106 5 610 92 9 1.20 0.91–1.57 1.34 0.99–1.81 0.64 0.21–1.93 0.029
Plaza-Izurieta 2011 Spain [7] 847 231 16 443 92 5 1.31 1.03–1.67 1.31 1.00–1.72 1.67 0.61–4.60 0.926
Overall OR 1.37 1.31–1.43 1.37 1.30–1.44 1.82 1.55–2.14

HWE: Hardy–Weinberg equilibrium.