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GL-1196 treatment showed the similar inhibitory effect on cell invasion by PAK4 knockdown. (A) the invasive ability of SGC7901 treated with GL-1196 and in which PAK4 knockdown was evaluated by chemotaxis chamber matrigel invasion assay. The magnification is 100×, and the number of invading cells is shown as bar diagram ± SEM (B left), ** p < 0.01. Western blot analysis shows the protein level of PAK4 in cells (B right).
