Table 3.

Criteria for inclusion and exclusion of patients.

Inclusion Criteria:	Exclusion Criteria:
Out-patient clinic recruitment (Of 202 recruited patients who participated in a genotype-phenotype multiple sclerosis (MS) study 92 patients were included into this study by random.)	–
Informed consent (in accordance with the approval requirements of the local ethics committee.)	–
Clinical stability (magnetic resonace imaging (MRI) scan of patients with an acute relapse was postponed for at least 30 days after the last dose of steroid treatment.)	–
–	Motion artefacts (This concerned 3/92 patients.)
Lesional volume alterations (This concerned 69/92 patients.)	Volumetric stability over the 12 month observation period (This concerned 20/92 patients.)