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. 2016 Apr 6;17(4):506. doi: 10.3390/ijms17040506
OS Osteosarcoma
SRC Steroid receptor co-activator
PD-1 Programmed cell death 1
PD-L1 Programmed cell death ligand 1
RB1 Retinoblastoma 1
TP53 Tumor protein p53
APEX1 Apurinic/Apyrimidinic exonuclease 1
BMPR2 Bone morphogenetic protein type II receptor
HMGB1 High mobility group box1
RANKL Receptor activator of nuclear factor-κB ligand
OPG Osteoprotegerin
RTKs Receptor tyrosine kinases
PDGFR Platelet-derived growth factor receptor
VEGFR Vascular endothelial growth factor receptor
IFNs Interferons
MAP Methotrexate, doxorubicin, and cisplatin
EFS Event-free survival
GM-CSF Granulocyte-macrophage colony-stimulating factor
MDP Muramyl dipeptide
MTP-PE Muramyl tripeptide phosphatidyl ethanolamine
IL Interleukin
TNF Tumor necrosis factor
PI3 Phosphatidylinositol 3
Erk Extracellular signal regulated kinase
IGF-R Insulin-Like Growth Factor Receptor
IGF Insulin-Like Growth Factor
MAPK Mitogen-activated protein kinase
PDGF/PDGFR Platelet-Derived Growth Factor/receptors
RCC Renal cell carcinoma
GIST Gastrointestinal stromal tumor
FLT-3 Fms-related tyrosine kinase-3
HCC Hepatocellular carcinoma
CML Chronic myeloid leukemia
ALL Acute lymphoblastic leukemia
AURK Aurora Kinase
ROS Reactive Oxygen Species
AMPK 5′ Adenosine monophosphate-activated protein kinase
RANK/RANKL Receptor activator of nuclear factor-κB/Ligand
ROCK1 Rho-associated, coiled-coil-containing protein kinase 1
NK Natural killer
nab Nanoparticle albumin-bound
MBC Metastatic breast cancer
TS Thymidylate synthase
GARFT Glycinamide ribonucleotide formyl transferase