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. 2016 Apr 7;17(4):522. doi: 10.3390/ijms17040522

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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IL-17A differentially induces inflammatory gene expression in the adipose tissues of lean and obese mice. (A–I) Adipose tissues were cultured in serum-free Dulbecco’s Modified Eagle Medium (DMEM) and treated without (−) or with (+) 20 ng/mL IL-17A for 2 h; mRNA expression of each gene was analyzed with qRT-PCR; SAT without IL-17A treatment served as the basal level for comparison; data represent mean ± SEM (error bars), n = 6 per group; ^a p < 0.05, compared to the untreated SAT group; ^b p < 0.05, compared to the lean mice; ^c p < 0.05, comparison between the untreated and IL-17A-treated groups.

IL-17A differentially induces inflammatory gene expression in the adipose tissues of lean and obese mice. (A–I) Adipose tissues were cultured in serum-free Dulbecco’s Modified Eagle Medium (DMEM) and treated without (−) or with (+) 20 ng/mL IL-17A for 2 h; mRNA expression of each gene was analyzed with qRT-PCR; SAT without IL-17A treatment served as the basal level for comparison; data represent mean ± SEM (error bars), n = 6 per group; ^a p < 0.05, compared to the untreated SAT group; ^b p < 0.05, compared to the lean mice; ^c p < 0.05, comparison between the untreated and IL-17A-treated groups.