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. 2016 Apr 11;17(4):542. doi: 10.3390/ijms17040542

Figure 2.

Figure 2

Increased myocardial apoptosis and ROS generation in SMP30 KO mice: (A) Representative images of DHE staining of frozen left ventricular tissues 30 min after I/R or sham operation in SMP30 KO and WT mice; (B) Quantitative analysis of intensity of DHE fluorescent. Data are reported as mean ± SE (n = 6). DHE, dihydroethidium. Scale bars: 100 μm. * p < 0.05 vs. sham-operated mice, and p < 0.05 vs. WT I/R mice; (C) Representative TUNEL-stained sections from WT and SMP30 KO mice subjected to 30 min of ischemia and 24 h of reperfusion or sham operation; (D) Percentages of TUNEL-positive nuclei in sections from WT and SMP30 KO mice. Data are reported as mean ± SE (n = 6). TUNEL, TdT-mediated dUTP nick end-labeling. Scale bars: 200 μm. * p < 0.05 vs. sham-operated mice.