Table 1.
Echocardiografic Parameter | WT Sham | SMP30 KO Sham | WT I/R | SMP30 KO I/R |
---|---|---|---|---|
IVSd (mm) | 0.75 ± 0.05 | 0.73 ± 0.06 | 0.73 ± 0.05 | 0.73 ± 0.04 |
LVPWd (mm) | 0.71 ± 0.03 | 0.72 ± 0.07 | 0.74 ± 0.05 | 0.71 ± 0.04 |
LVEDd (mm) | 3.01 ± 0.11 | 3.08 ± 0.08 | 2.92 ± 0.31 | 2.87 ± 0.32 |
LVESd (mm) | 1.42 ± 0.07 | 1.45 ± 0.05 | 1.65 ± 0.28 ** | 1.81 ± 0.30 **,# |
LVFS (%) | 52.8 ± 2.1 | 53.0 ± 1.6 | 43.4 ± 5.1 ** | 37.3 ± 4.3 **,# |
HR (bpm) | 499 ± 37 | 520 ± 44 | 478 ± 46 | 509 ± 25 |
IVSd, interventricular septum diameter; LVPWd, left ventricular posterior wall diameter; LVEDd, left ventricular end-diastolic dimension; LVESd, left ventricular end-systolic dimension; LVFS, left ventricular fractional shortening; HR, heart rate. Data are presented as mean ± SD from 10 to 15 mice in each group. ** p < 0.01 vs. sham-operated mice, and # p < 0.05 vs. WT I/R mice.