RCC |
renal cell carcinoma |
ccRCC |
clear-cell RCC |
pRCC |
papillary RCC |
chRCC |
chromophobe RCC |
VHL |
von-Hippel-Lindau |
HIF |
hypoxic-inducible factor |
PBRM1 |
protein polybromo 1 |
BAP1 |
BRCA1 associated protein-1 |
SETD2 |
SET domain containing 2 |
CSS |
cancer-specific survival |
HLRCC |
hereditary papillary RCC and as hereditary leiomyomatosis and RCC |
MET |
met proto-oncogene |
CDKN2A |
cyclin-dependent kinase Inhibitor 2A |
TFE3 |
transcription factor E3 |
NRF2 |
nuclear factor-like 2 |
TP53 |
tumour protein p53 |
PTEN |
phosphatase and tensin homolog |
VEGF |
vascular endothelial growth factor |
mTOR |
mammalian target of rapamycin |
PD1 |
programmed cell death protein 1 |
OS |
overall survival |
PDGF |
platelet derived growth factor |
lncRNAs |
long non-coding RNAs |
XIST |
RNA gene on the X chromosome |
HOTAIR |
HOX antisense intergenic RNA |
H19 |
H19 gene |
TERRA |
telomeric repeat-containing RNA |
MALAT1 |
metastasis-associated lung adenocarcinoma transcript 1 |
PTENP1 |
phosphatase and tensin homolog pseudogene 1 |
PCR |
polymerase chain reaction |
MITF/TFE |
microphthalmia-associated transcription factor |
TCGA |
the Cancer Genome Atlas |
TNM |
tumour, node, metastasis classification system |
EZH2 |
enhancer of zeste homolog 2 |
PRC2 |
polycomb repressive complex 2 |
siRNA |
small interfering RNA |
mRNA |
messenger RNA |
NEAT2 |
nuclear-enriched abundant transcript 2 |
EMT |
epithelial-to-mesenchymal transition |
TCF/LEF |
T-cell factor/lymphoid enhancer factor transcription factors |
ceRNA |
competing endogenous RNA |
ZEB2 |
zinc finger E-box-binding homeobox 2 |
HIF |
hypoxic inducible factor |
GAS5 |
growth arrest specific 5 |
cIAP2 |
Baculoviral IAP repeat-containing protein 3 |
CDK6 |
cell division protein kinase 6 |
pcDNA |
DNA vector used to clone recombinant DNA sequences |
MEG3 |
maternally expressed gene 3 |
BCL2 |
B-cell lymphoma 2 |
SPRY4-IT1 |
protein sprouty homolog 4 intronic transcript 1 |
MAPK |
mitogen-activated protein kinase |
CADM1-AS1 |
Cell adhesion molecule 1 anti-sense transcript 1 |
RCCRT1 |
renal cell carcinoma related transcript 1 |
NBAT1 |
neuroblastoma associated transcript 1 |
Neat1 |
nuclear-enriched abundant transcript 1 |
Fendrr |
Foxf1 adjacent non-coding developmental regulatory RNA |