Table 3.

Summary of the proteins altered expression from postmortem proteomic investigations of bipolar disorder. Downregulated (↓), upregulated (↑).

			References
Protein Name	Gene Symbol	Uniprot acc. No.	[26]	[24]	[31]	[18]	[39,40]	[41]
Actin isoforms	ACTB	P60709					↑
Actin-related protein 2/3 complex components	ARPC5	O15511					↑
Dihydropyrimidinase-related protein isoforms	CRMP1	Q14194	‒		‒	‒	‒
	DPYSL2	Q16555	↓		‒	↑	↓
	DPYSL3	Q14195			↑	↑	↓
Dynactin subunit 2	DCTN2	Q13561					↓
Dynamin-1	DNM1	Q05193					↓
Fascin	FSCN1	Q16658					↓
Glial fibrillary acidic protein	GFAP	P14136	↓
Α-internexin	INA	Q16352			↓		↓
Kinesin light chain 2	KLC2	Q9H0B6			↑
Microtubule-associated protein isoforms	MAP1LC3A	Q9H492
Neurofilament intermediate proteins	NEFL	P07196			‒	‒	↓	↓
	NEFM	P07197			↓	↑	↓
	NEFH	P12036				↓
Septin isoforms	SEPT3	Q9UH03	‒		‒		‒
	SEPT5	Q99719			↑		‒
	SEPT6	Q14141			↑		‒
	SEPT11	Q9NVA2			↑		↓
Spectrin α chain, non-erythrocytic 1	SPTAN1	Q13813					↓
Stathmin	STMN1	P16949					↑
Tubulin isoforms	TBBX	P07437		↓	‒
	TUBA1B	P68363			↑
	TUBA4B	Q9H853			‒
	TUBB1	Q9H4B7			↑
T-complex protein 1 subunit α	TCP1	P17987			↑
Tropomyosin isoforms	TPM4	P67936					↓
Vimentin	VIM	P08670				↑	↓
Programmed cell death 6-interacting protein	PDCD6IP	Q8WUM4				↑
WD repeat-containing protein 1	WDR1	O75083					↓