Table 1.
Comparison of the clinical characteristics and serum lipid levels between controls and patients.
| Parameter | Control | CHD | IS | p1 | p2 |
|---|---|---|---|---|---|
| Number | 541 | 565 | 569 | – | – |
| Male, n (%) | 346 (64.0) | 394 (69.7) | 396 (69.6) | 0.051 | 0.053 |
| Age, years | 61.39 ± 11.41 | 62.31 ± 10.53 | 62.53 ± 11.92 | 0.079 | 0.051 |
| Body mass index, kg/m2 | 22.49 ± 2.90 | 23.98 ± 3.21 | 23.50 ± 3.60 | 0.000 | 0.000 |
| Cigarette smoking, n (%) | 217 (40.1) | 244 (43.2) | 258 (45.7) | 0.300 | 0.078 |
| Diabetes, n (%) | 19 (3.5) | 129 (22.8) | 305 (53.98) | 0.000 | 0.000 |
| Hypertension, n (%) | 123 (22.7) | 282 (49.9) | 326 (57.3) | 0.000 | 0.000 |
| Hyperlipidemia, n (%) | 229 (42.3) | 277 (49.0) | 84 (14.9) | 0.025 | 0.000 |
| Total cholesterol, mmol/L | 4.84 ± 1.07 | 4.55 ± 1.24 | 4.52 ± 1.16 | 0.002 | 0.000 |
| Triglyceride, mmol/L | 1.01 (0.69) | 1.34 (0.93) | 1.36 (0.94) | 0.000 | 0.000 |
| HDL-C, mmol/L | 1.85 ± 0.51 | 1.14 ± 0.34 | 1.24 ± 0.41 | 0.000 | 0.000 |
| LDL-C, mmol/L | 2.77 ± 0.82 | 2.73 ± 1.04 | 2.67 ± 0.91 | 0.511 | 0.071 |
| Apolipoprotein (Apo)A1, g/L | 1.37 ± 0.28 | 1.05 ± 0.55 | 1.05 ± 0.55 | 0.000 | 0.000 |
| ApoB, g/L | 0.89 ± 0.21 | 0.90 ± 0.28 | 0.90 ± 0.26 | 0.344 | 0.431 |
| ApoA1/ApoB | 1.62 ± 0.55 | 1.40 ± 2.51 | 1.19 ± 0.60 | 0.042 | 0.000 |
CHD, coronary heart disease; IS, ischemic stroke; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. The value of triglyceride was presented as median (interquartile range), the difference between CHD/IS patients and controls was determined by the Wilcoxon-Mann-Whitney test. p1, CHD vs. controls; p2, IS vs. controls.