Table 6.
Gene–gene interactions on the risk of IS.
| Model | MDR Analysis | LR Analysis | |||||
|---|---|---|---|---|---|---|---|
| Traing Bal.Acc | Testing Bal.Acc | CVC | p | Wald | OR (95% CI) | p | |
| rs2740483 | 0.557 | 0.555 | 10/10 | 0.001 | - | - | - |
| A-B | 0.603 | 0.602 | 10/10 | 0.001 | 20.56 | 1.80 (1.40–2.32) | 0.000 |
| A-B-C | 0.624 | 0.594 | 8/10 | 0.011 | 13.56 | 1.19 (0.90–1.27) | 0.000 |
| A-B-C-rs2740483 | 0.654 | 0.602 | 10/10 | 0.001 | 0.22 | 1.02 (0.94–1.40) | 0.640 |
A, rs1333040; B, rs1333042; C, rs4977574; p value based on 1000 permutations; CVC, Cross-validation consistency; LR analysis, Logistic regression analysis.