. 2016 Apr 19;17(4):593. doi: 10.3390/ijms17040593

Table 1.

Overview of the relevant literature concerning the role of sEGFR in NSCLC.

Researcher	Population	sEGFR Detection Method	Main Findings
Lemos-Gonzalez 2007 [61]	25 NSCLC vs. 50 healthy donors	ELISA (R&D system)	Significant lower sEGFR values in NSCLC-patients.
Jantus-Lewintre 2011 [62]	308 NSCLC vs. 109 healthy donors	ELISA (R&D system)	Significant lower sEGFR values in NSCLC-patients.
Jantus-Lewintre 2011 [62]	308 NSCLC vs. 109 healthy donors	ELISA (R&D system)	sEGFR as a significant independent prognostic marker.
Maramotti 2012 [50]	12 NSCLC vs. 12 healthy donors	ELISA (Ray Boitech)	Significant lower sEGFR values in NSCLC-patients.
Lococo 2015 [51]	37 not-advanced NSCLC vs. 54 healthy donors	ELISA (R&D system)	sEGFR inhibits growth and migration of NSCLC cells in vitro.
Lococo 2015 [51]	37 not-advanced NSCLC vs. 54 healthy donors	ELISA (R&D system)	Significant lower sEGFR values in NSCLC-patients.