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. 2016 Apr 22;17(4):609. doi: 10.3390/ijms17040609

Figure 3.

Figure 3

Knockdown of m-Trim46 inhibited cell proliferation and metastasis. (A) The expression of Trim46 in the m-Trim46-shRNA stable expression 4TO7 cell line was determined by western blot. GAPDH was used for normalization. *** indicates p < 0.001 versus control; (B) Growth curves of mTrim46-shRNA stable expression cell lines at indicated time. * indicates p < 0.05; *** indicates p < 0.001 versus control; (C) Representative photos of lung metastasis nodules of mTrim46-shRNA stable expression cell lines; and (D) The number of metastasis nodules in (D) was calculated (n = 6 for control; n = 8 for mTrim46-shRNA). ** indicates p < 0.01 versus control.