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Teratogenicity of hapalindole-type alkaloids in the zebrafish (Danio rerio) embryo as a model of vertebrate development. Shown are control (untreated) embryos at 3 days post-fertilization (a); and embryos exposed for three days to 12-epi-ambiguine B nitrile at 10 μg/mL (b); and to 12-epi-hapalindole H isonitrile at 5 and 10 μg/mL (c and d, respectively) [61].
