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. 2016 Apr 27;17:189. doi: 10.1186/s12859-016-1060-3

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© Hess et al. 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Comparison of CorBLOSUM61 _5.0 with BLOSUM62 _5.0 and RBLOSUM64 _5.0. Differences between CorBLOSUM61 _5.0 and BLOSUM62 _5.0 are displayed in the lower triangle and those between CorBLOSUM61 _5.0 and RBLOSUM64 _5.0 in the upper triangle, with CorBLOSUM61 _5.0 values shown. Light gray tiles represent entries where the CorBLOSUM61 _5.0 matrix is one log-odd score point higher than the compared matrix, whereas dark gray represent a one point lower score of CorBLOSUM61 _5.0 matrix. Noticeably, the CorBLOSUM correction introduces further changes into the RBLOSUM64 _5.0 matrix (upper triangle) which results in numerous value adjustments when compared to the BLOSUM62 _5.0 matrix (lower triangle)