Figure 2.

Control (Ctrl) recipient mice transplanted with mutant (Mut) bone marrow (BM) cells had higher muscularization compared with Mut mice transplanted with Ctrl BM cells. (A) Lung sections of recipient mice were stained with anti–smooth muscle actin antibody (fluorescein isothiocyanate conjugated) and visualized by immunofluorescence 16 weeks after transplantation. (B) Three different-sized vessels were counted from 10 microscope fields. Data are presented as means ± SEM and were analyzed by Student's t test. P values less than 0.05 were considered statistically significant. Analyses were performed with Prism 5 for Mac OS X (GraphPad Software Inc., La Jolla, CA).