Table 2.
History, Immune Diagnosis, and Outcome at the Next Embryo Transfer in the RIF Cohort of 394 Patients
| Immune endometrial diagnosis in the RIF cohort | Over immune endometrial activation | Low immune endometrial activation | No immune dysregulation | P value (anova) |
|---|---|---|---|---|
| Number of RIF patients | 223 (56.6%) | 99 (25%) | 72 (18.3%) | |
| Mean age (years) | 36.6 | 37.1 | 37 | 0.24 |
| Number of previous attempt | 3.3 | 3.3 | 3.3 | 0.29 |
| Years of infertility | 6.3 | 6.5 | 6.7 | 0.50 |
| Number of embryos previously transferred | 8.8 | 8.8 | 9.1 | 0.89 |
| Implantation rate (3 weeks) | 29% | 36% | 19% | 0.01 |
| Implantation rate (10 weeks) | 24.7% | 32% | 15% | 0.009 |
| Clinical PR at the first following ET (3 weeks) | 47.1% (105/223) | 55.6% (56/99) | 30.6% (22/72) | 0.005 |
| Ongoing PR at the first following ET (10 weeks) | 37.7% (84/223) | 48.5% (48/99) | 20.8% (15/72) | 0.001 |
| LBR at the first following ET | 36.8% (82/223) | 46.5% (46/99) | 19.4% (14/72) | 0.001 |
| Early miscarriage rates | 9% (21/223) | 8% (8/99) | 9.7% (7/72) | 0.42 |
RIF, Repeated embryo Implantation Failures; PR, Pregnancy Rate; ET, Embryo Transfer.
A P‐value <0.05 was considered statistically significant.