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NTSp colonizes the chinchilla nasopharynx with minimal ascension into the middle ear. Chinchillas were inoculated intranasally with NTSp strain MNZ1113. Pneumococcal bacterial loads were quantitated at one, four and seven days post-inoculation in the nasopharynx (A), Eustachian tubes (B) and middle ear bullae (C). Dotted line indicates limit of detection.
