Table 3. Vascular and metabolic parameters.
|
Schizophrenia (N) |
Control (N) |
P-value | |||
|---|---|---|---|---|---|
| Total sample | 51 |
51 |
— | ||
| Mean | s.d. | Mean | s.d. | ||
|
Vascular parameters | |||||
| Velocity time integral (cm) | 104.9 | 33.0 | 129.1 | 33.8 | <0.001 |
| Flow-mediated dilation (%) | 7.1 | 4.8 | 7.1 | 3.8 | 0.933 |
| Pulse arterial tonometry | 1.94 | 0.58 | 1.92 | 0.43 | 0.862 |
| Baseline diameter of brachial artery (cm) | 4.06 | 0.671 | 3.97 | 0.636 | 0.488 |
|
Metabolic parameters | |||||
| Total cholesterol (mmol/l) | 4.72 | 0.82 | 4.37 | 0.73 | 0.028 |
| HDL-cholesterol (mmol/l) | 1.15 | 0.30 | 1.49 | 0.46 | <0.001 |
| LDL-cholesterol (mmol/l) | 2.71 | 0.79 | 2.38 | 0.69 | 0.033 |
| Glucose fasting (mmol/l) | 5.24 | 1.07 | 4.79 | 0.36 | 0.007 |
| Hemoglobin A1c (%) | 5.65 | 0.29 | 5.39 | 0.28 | <0.001 |
| Hemoglobin (g/l) | 148 | 14 | 150 | 13 | 0.415 |
| Median | 25th , 75th percentile | Median | 25th , 75th percentile | ||
|---|---|---|---|---|---|
| Creatinine (μmol/l) | 77 | 21 | 77 | 15 | 0.890 |
| High-sensitivity C-reactive protein (mg/l) | 1.50 | (0.70, 3.22) | 0.80 | (0.40, 1.22) | 0.003 |
| Insulin (pmol/l) | 58.9 | (42.9, 96.4) | 34.8 | (22.6, 42.6) | <0.001 |
| HOMA-IR | 1.82 | (1.25, 3.36) | 1.04 | (0.66, 1.34) | <0.001 |
| Triglycerides (mmol/l) | 1.61 | (1.11, 2.57) | 0.88 | (0.67, 1.21) | <0.001 |
Abbreviations: HDL, high-density lipoprotein; HOMA-IR, homeostatic model assessment-insulin resistance; LDL, high-density lipoprotein.