Table 2. Summary of significant brain activation differences between UHR individuals and controls during neutral image processing versus fixation, negative image processing versus neutral image processing, and reappraisal versus negative image processing.
| Brain region | Hemisphere | k voxels |
MNI coordinates
|
Z | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
|
View Neutral>Fixation
| ||||||
| Controls>UHR | ||||||
| Temporal pole | L | 158 | −36 | 22 | −22 | 5.34 |
| −28 | 12 | −24 | 4.11 | |||
| Posterior cingulate gyrus | R/L | 273 | 8 | −50 | 28 | 4.23 |
| −4 | −26 | 22 | 3.99 | |||
| 0 | −40 | 18 | 3.80 | |||
|
View Negative >View Neutral
| ||||||
| UHR >Controls | ||||||
| Posterior cingulate gyrus | R/L | 144 | −6 | −52 | 30 | 3.73 |
| 8 | −50 | 28 | 3.67 | |||
| 0 | −42 | 32 | 3.64 | |||
|
Reappraise >Attend Negative
| ||||||
| Controls >UHR | ||||||
| Inferior frontal gyrus triangular part | L | 168 | −46 | 26 | 12 | 4.76 |
Abbreviation: UHR, ultrahigh risk group.