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. 2016 Apr 28;11(4):e0152911. doi: 10.1371/journal.pone.0152911

Fig 6. Simulation study with normal and depressed LV systolic function.

Fig 6

(A): Simulated PV loop of LV with normal (solid line, maximum elastance: 7 mmHg/ml) and depressed (dashed line, maximum elastance: 1 mmHg/ml) systolic function. Mean circulatory filling pressure was fixed in both systolic conditions (6.4 mmHg). (B): The relationship between LVAD support flow and changes in PVA in normal (solid line) and depressed (dashed line) LV systolic function. PVA at baseline (no LVAD support) were normalized at 100% in each group. Both “a” and “b” indicate the inflection point which circulation turns to total LVAD from partial LVAD support. The rate of decrease in PVA by partial LVAD support (baseline PVA to that of “a” and “b”) is much lower in depressed LV (-27%) than in normal LV (-54%).