Table 1. Impact of level of left ventricular assist device (LVAD) support on hemodynamics in normal dogs.
| HR | CO | LVAD flow | CBF | MAP | LVEDP | Peak LVP | RAP | LAP | ESV | EDV | SCSO2 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (bpm) | (l/min) | (l/min) | (ml/min) | (mmHg) | (mmHg) | (mmHg) | (mmHg) | (mmHg) | (ml) | (ml) | (%) | |
| Control | 119±12 | 1.19±0.27 | 0 | 14.3±2.5 | 98±12 | 5.5±2.1 | 111±9 | 3.52±2.36 | 8.25±1.62 | 25.5±7.1 | 37.4±5.4 | 41.9±5.4 |
| p-LVAD | 122±9.1 | 0.58±0.12* | 0.71±0.13* | 13.3±3.1 | 105±10* | 4.2±1.9* | 118±20 | 3.63±2.29 | 7.26±2.00 | 25.0±7.0 | 33.8±6.3* | 49.9±8.7 |
| t-LVAD | 122±7.8 | 0*† | 1.46±0.30*† | 12.4±5.5 | 110±7*† | 1.2±1.0*† | 30±19*† | 3.67±2.02 | 3.63±1.78*† | 22.0±5.8*† | 27.1±6.2*† | 67.7±7.1*† |
Data are expressed as means ± SD. Control, no LVAD support; p-LVAD, partial LVAD support; t-LVAD, total LVAD support; HR, heart rate; CO, cardiac output; LVAD flow, flow of left ventricular assist device; CBF, coronary (LAD) blood flow; MAP, mean arterial pressure; LVEDP, left ventricular end-diastolic pressure; Peak LVP, peak LV pressure; RAP, right atrial pressure; LAP, left atrial pressure; ESV, end systolic volume; EDV, end diastolic volume; SCSO2, oxygen saturation in coronary sinus vein.
* p < 0.05 versus Baseline;
† p < 0.05 versus p-LVAD.