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. 2016 Apr 28;11(4):e0153765. doi: 10.1371/journal.pone.0153765

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© 2016 Roderburg et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (a) Critically ill patients with sepsis (n = 84) displayed significantly lower TWEAK serum concentrations (n = 37, U-test) compared to patients without sepsis. (b) TWEAK serum concentrations were not different in patients with different etiologies of critical illness and are highest in patients with cardiac diseases. (c) ROC curve analyses comparing the diagnostic power in predicting sepsis of TWEAK with well-established laboratory markers: C-reactive protein (CRP), procalcitonin, and white blood cell count (leukocytes).