Table 3. Comparison of clinical characteristics between patients with secondary peritonitis and intra-abdominal abscess.
| Parameter | Secondary Peritonitis (n = 53) | Abscess (n = 89) | P value |
|---|---|---|---|
| Age in years, median (range) | 60 (23–90) | 59 (21–88) | 0.95 |
| Male sex | 29 (55) | 43 (48) | 0.46 |
| Immunocompromised | 18 (34) | 20 (23) | 0.14 |
| Site of origin1 | |||
| Gastric/Duodenum | 10 (19) | 16 (18) | 0.89 |
| Jejunum/Ileum | 19 (36) | 12 (14) | 0.002 |
| Colon | 15 (28) | 31 (35) | 0.42 |
| Liver/Gallbladder | 6 (11) | 12 (14) | 0.71 |
| Pancreas | 3 (6) | 17 (19) | 0.03 |
| Prior intra-abdominal surgery | 26 (49) | 56 (63) | 0.11 |
| Healthcare-associated IAC | 41 (77) | 72 (81) | 0.61 |
| Septic shock | 12 (23) | 10 (11) | 0.07 |
| Perforation2 | 29 (55) | 42 (47) | 0.39 |
| Bacterial co-infection | 33 (62) | 68 (76) | 0.07 |
| C. glabrata infection | 19 (36) | 20 (23) | 0.08 |
| Candidemia | 3/4 (7) | 4 (6) | 1.00 |
| Recurrence/Persistence | 4 (8) | 7 (8) | 1.00 |
| 100-day mortality | 21 (40) | 15 (17) | 0.003 |
Data are presented in absolute numbers (percentages), unless otherwise indicated.
1Site of origin in one female patient with intra-abdominal abscess was the genital tract.
2Rates of Candida infection by site of perforation during the study period were: stomach (39%, 12/31), duodenum (22%, 8/37), jejunum/ileum (25%, 17/69), colon (19%, 32/172), and appendix (4%, 2/50).