Table 5. Predictors of 100-day mortality for subjects with IAC stemming from GI tract sources.
| Parameter | Non-survivors (n = 26) | Survivors (n = 77) | Univariate OR (95% CI) | Univariate P value | Multivariate OR (95% CI) | Multivariate P value |
|---|---|---|---|---|---|---|
| Age, median (interquartile range) | 68 (58–77) | 58 (46–68) | 1.04 (1.01–1.08) | 0.01 | 1.04 (1.01–1.08) | 0.018 |
| Male | 15 (58) | 32 (42) | 1.92 (0.78–4.72) | 0.16 | ||
| Solid organ transplant | 3 (12) | 4 (5) | 2.38 (0.50–11.43) | 0.28 | ||
| Obesity (BMI >30) | 11 (42) | 18 (23) | 21.84 (0.67–5.02) | 0.07 | … | … |
| Healthcare-associated disease | 20 (77) | 61 (79) | 0.87 (0.30–2.54) | 0.81 | ||
| APACHEII score | 17 (7–27) | 16 (5–29) | 1.04 (0.94–1.14) | 0.47 | ||
| Septic shock | 6 (23) | 11 (14) | 1.8 (0.59–5.48) | 0.30 | ||
| Perforation | 19 (73) | 51 (66) | 1.38 (0.52–3.71) | 0.52 | ||
| Presence of abscess | 11 (42) | 48 (62) | 0.44 (0.18–1.09) | 0.08 | 0.36 (0.13–0.96) | 0.042 |
| Bacterial co-infection | 16 (62) | 57 (74) | 0.56 (0.22–1.44) | 0.23 | ||
| C. glabrata infection | 7 (27) | 23 (30) | 0.86 (0.32–2.34) | 0.78 | ||
| Candidemia | 0/19 | 3/57 (5) | 0.57 | |||
| Surgical intervention | 19 (73) | 50 (65) | 1.47 (0.55–3.92) | 0.45 | ||
| Surgical intervention (within 5d) | 15 (58) | 42 (55) | 1.55 (0.63–3.81) | 0.78 | ||
| Source control intervention (within 5d) | 17 (65) | 63 (82) | 0.49 (0.20–1.22) | 0.09 | … | … |
| Antifungal treatment (within 5d) | 13 (50) | 56 (73) | 0.38 (0.15–0.94) | 0.04 | 0.36 (0.13–0.96) | 0.042 |
| Infectious disease consultation | 6 (23) | 28 (36) | 0.53 (0.19–1.46) | 0.22 |
Data are presented in absolute numbers (percentages), unless otherwise indicated. Variables in ellipsis were removed from the multivariate analysis using backward elimination.
Abbreviation: OR, odds ratio.