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. 2016 Apr 28;11(4):e0154101. doi: 10.1371/journal.pone.0154101

Table 1. Susceptibility to miltefosine (MIL) of the different L. infantum strains.

Strain Intracellular amastigotes IC50 (mean ± SEM) Promastigotes IC50 (mean ± SEM)
LEM3323 2.3 ± 0.5 5.3 ± 0.3
LEM3323-MIL >20.0 >40.0
LEM3323-MIL + LiMT 3.0 ± 1.0 2.4 ± 1.2
LEM3049 0.8 ± 0.4 5.6 ± 1.1
LEM5159 > 20.0 > 40.0
LEM5159 + LiRos3 0.5 ± 0.3 3.8 ± 1.3
LEM5159 + LiMT > 20.0 > 40.0
ΔLdMT > 20.0 > 40.0
ΔLdMT + LiMTGFP 3.5 ± 2.3 12.8 ± 0.8
ΔLdMT + LiMTE926QGFP 4.3 ± 1.6 16.1 ± 0.8

Li: L. infantum; Ld: L. donovani