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. 2016 Apr 28;12(4):e1006010. doi: 10.1371/journal.pgen.1006010

Fig 6. Deletion alleles of MAP kinase pathway components suppress the muscle arm extension defects of madd-3 mutants.

Fig 6

A. Shown are the muscle arm defects of deletion alleles (as indicated by the ok, gk, or tm prefix) of the indicated MAP kinase component. B. Muscle-specific expression of SEK-3 (from the him-4 promoter from construct pPRSAD936) is able to rescue sek-3(ok1276)’s suppression of madd-3(tr186)’s muscle arm defects. C. Muscle-specific over-expression of CEBP-1 (from the him-4 promoter from construct pPRSAD961) phenocopies the madd-3(tr186) mutant phenotype from three distinct transgenic lines. For A-C, the presence of a wild type or tr186 allele of MADD-3A is indicated with a respective (+) or (-) below the bars of the graph. In graphs A and C, counts for ventral left muscle 11 are shown, and in B, counts for dorsal right 15 is shown. In all graphs, an asterisk indicates a significant difference (p<0.01) compared to the data point indicated with a closed circle of the same color as the asterisks.