Table 1. A summary of the inter-observer repeatability results.
All values in bold represent the mode estimate from the estimates distribution of each metric, with 95% confidence intervals displayed in parentheses. All measurements assume ADC units of 10−3 mm2/s and estimates of σab and CoV are displayed following multiplication by a factor 100 for clarity. Note that the percentage repeatability indicates the change in each parameter that would be needed for statistically significant change. Whilst repeatability is excellent for mean/median gADC and log-tDV estimates, poorer reproducibility is found for higher order gADC statistics.
| WB-DWI parameter | σab (×100) (95% CI) | CoV (×100) (95% CI) | % Repeatability (95% CI) |
|---|---|---|---|
| Median gADC | 1.81 (0.89–3.72) | 1.98 (0.97–4.13) | 5.48 (2.70–11.5) |
| Mean gADC | 2.39 (1.27–4.81) | 2.54 (1.34–5.13) | 7.05 (3.72–14.2) |
| log-tDV | 13.2 (5.99–30.1) | 3.19 (1.40–8.05) | 8.84 (3.88–22.3) |
| gADC variance | 0.95 (0.41–2.02) | 13.6 (5.97–31.1) | 37.8 (16.6–86.1) |
| gADC skewness | 6.32 (2.73–16.7) | 9.09 (3.52–29.8) | 25.1 (9.77–82.7) |
| gADC kurtosis | 33.7 (13.9–71.6) | 8.81 (3.46–19.4) | 24.4 (9.59–53.9) |