. 2015 Oct 29;27(5):1487–1494. doi: 10.1681/ASN.2014090876

Table 1.

Incidence ratios of ESRD due to multiple myeloma requiring RRT, 2001–2010

	Analysis of the Overall Population			Standardized Incidence Ratios within Subgroups (versus 2001–2002)
		Incidence Ratios
	Cases/Rate (PMPY)	Crude	Standardized	2003–2004	2005–2006	2007–2008	2009–2010
All	12,703 (4.3)	—	—	0.96 (0.92–0.99)^b	0.99 (0.95–1.03)^a	0.89 (0.86–0.92)	0.82 (0.79–0.86)
2001–2002	2557 (4.5)	1 (Reference)	1 (Reference)	—	—	—	—
2003–2004	2517 (4.3)	0.99 (0.95–1.03)^a	0.96 (0.92–0.99)^b	—	—	—	—
2005–2006	2696 (4.6)	0.99 (0.96–1.03)^a	0.99 (0.95–1.03)^a	—	—	—	—
2007–2008	2512 (4.2)	0.93 (0.89–0.97)	0.89 (0.86–0.92)	—	—	—	—
2009–2010	2421 (3.9)	0.85 (0.82–0.88)	0.82 (0.79–0.86)	—	—	—	—
Age <40	172 (0.1)	0.06 (0.06–0.07)	0.06 (0.05–0.07)	1.08 (0.74–1.58)^a	1.36 (0.96–1.93)^a	1.44 (1.01–2.04)^b	1.28 (0.89–1.82)^a
Age 40–64	4448 (2.3)	1 (Reference)	1 (Reference)	1.03 (0.96–1.1)^a	1.11 (1.04–1.18)^c	0.97 (0.91–1.04)^a	0.93 (0.87–1)^b
Age ≥65	8083 (10.8)	4.65 (4.53–4.77)	4.99 (4.86–5.12)	0.92 (0.87–0.96)	0.93 (0.88–0.97)^c	0.84 (0.8–0.88)	0.76 (0.73–0.8)
Male	7139 (3.5)	1.18 (1.15–1.2)	1.6 (1.56–1.64)	0.95 (0.9–1)^a	1.04 (0.99–1.1)^a	0.99 (0.94–1.04)^a	0.89 (0.85–0.94)
Female	5564 (3)	1 (Reference)	1 (Reference)	0.96 (0.91–1.02)^a	0.93 (0.88–0.99)^b	0.78 (0.73–0.82)	0.74 (0.7–0.79)
White	9703 (2.9)	1 (Reference)	1 (Reference)	0.95 (0.91–1)^b	1 (0.96–1.05)^a	0.91 (0.87–0.95)	0.83 (0.79–0.87)
Black	2641 (6.3)	2.15 (2.08–2.21)	2.45 (2.37–2.52)	0.97 (0.89–1.05)^a	1 (0.92–1.09)^a	0.85 (0.78–0.93)	0.83 (0.76–0.9)
Other	359 (2.5)	0.83 (0.77–0.9)	0.77 (0.71–0.83)	0.89 (0.71–1.11)^a	0.61 (0.48–0.78)	0.69 (0.55–0.86)^c	0.57 (0.46–0.72)

Parameter estimates are rates PMPY or incidence ratios with standard errors with 95% confidence intervals in parentheses. Adjustment factors included age, sex, and race-ethnicity. P<0.001 unless otherwise indicated. Reference indicates the group used for statistical comparisons.

P≥0.05.

0.01≤P<0.05.

0.001≤P<0.01.