Table 5.

Associations between the E161K polymorphism and kidney stones estimated by mixed effects logistic regression models

Kidney Stones	Unadjusted		Sex		Age		BMI		Sex and Age		Sex and BMI		Age and BMI
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
Calcium oxalate (present)	0.57 (0.15 to 3.74)	0.47	0.62 (0.16 to 4.10)	0.54	1.06 (0.22 to 21.69)	0.88	1.32 (0.25 to 2.45)	0.79	1.21 (0.23 to 22.46)	0.86	1.34 (0.25 to 2.49)	0.78	1.3 (0.24 to 2.45)	0.80
Calcium phosphate (present)	3.71 (1.45 to 10.69)	<0.01	3.60 (1.37 to 10.57)	<0.05	2.89 (1.10 to 8.45)	<0.05	3.28 (1.23 to 9.69)	<0.05	2.90 (1.08 to 8.66)	<0.05	3.32 (1.21 to 10.04)	<0.05	2.78 (1.03 to 8.28)	<0.05
Uric acid (present)	<0.001	0.86	<0.001	0.87	<0.001	0.99	<0.001	0.96	<0.001	0.95	<0.001	0.31	<0.001	0.97

The estimate of E161K has the wild type as the reference group. The between-center variability was taken into account as a random effect in all models. Complete data of 365–388 kidney SFs were available for inclusion in the regression models. OR, odds ratio; 95% CI, 95% confidence interval.