Table 1.

Differences in AMD and aHUS overall risk scores

Groups Compared		Mean Overall Risk
AMD risk
aHUS R1210C carriers (n=13)		44.8 ± 25.3	44.8 ± 25.3
AMD cohort (n=259)		67.3 ± 20.8
Controls (n=191)			44.3 ± 21.1
	p-value	0.001	0.99
Healthy R1210C carriers (n=16)		49.9 ± 18.5	49.9 ± 18.5
AMD cohort (n=259)		67.3 ± 20.8
Controls (n=191)			44.3 ± 21.1
	p-value	0.004	0.56
R1210C AMD pedigrees (n=22)		60.6 ± 23.8	60.6 ± 23.8
AMD cohort (n=259)		67.3 ± 20.8
Controls (n=191)			44.3 ± 21.1
	p-value	0.33	0.002
aHUS risk
aHUS R1210C carriers (n=13)		2.46 ± 1.05	2.46 ± 1.05
R1210C AMD pedigrees (n=22)		0.38 ± 0.59
Healthy R1210C carriers (n=13)			0.88 ± 0.81
	p-value	<0.001	<0.001