Figure 1. In vivo Col5a1^+/- mice healed slower than Col5a1^+/+ mice.

In vivo wound healing studies showed that Col5a1^+/- mice healed slower than Col5a1^+/+ mice. Full thickness wounds (4 mm diameter) were made in the subscapular skin of 60 days old mice (n=4 for each genotype). Wound closure was photographed every 24hr and wound area was measured. (A) Wound areas were measured daily over a 10-day post wounding period. Wound healing was expressed as the percentage of wound area relative to the day 0 area (punched wound size) (**p<0.01). (B) Representative wound closure of Col5a1^+/- and Col5a1^+/+ mice at day 0 and day 5 after wounding was shown. A mm scale is pictured.