Table 7. Imidazopyrazines Merck Research Laboratories.
| ||
|---|---|---|
|
| ||
| Compd | R | IC50a (nM) |
| 58 |
|
650 |
| 59 |
|
60 |
Expressed as the inhibition of MK2 ability to phosphorylate a peptide substrate.
| ||
|---|---|---|
|
| ||
| Compd | R | IC50a (nM) |
| 58 |
|
650 |
| 59 |
|
60 |
Expressed as the inhibition of MK2 ability to phosphorylate a peptide substrate.