Table 1.
Erosions | |||||
---|---|---|---|---|---|
Block I | Block II | Block III | Block IV | Block V | |
Vehicle (n=8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) |
Ang II-L (n=10) | 1 ± 1.25 (5/10) | 0.7 ± 0.68* (6/10) | 0.4 ± 0.966 (2/10) | 0 ± 0 (0/10) | 0 ± 0 (0/10) |
Ang II-H (n=12) | 1.08 ± 0.9** (9/12) | 1.0 ± 1.04* (7/12) | 0.73 ± 0.65** (7/12) | 0 ± 0 (0/12) | 0 ± 0 (0/12) |
Ruptures | |||||
Block I | Block II | Block III | Block IV | Block V | |
Vehicle (n=8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) |
Ang II-L (n=10) | 0 ± 0 (0/10) | 0 ± 0 (0/10) | 0.1±0.316 (1/10) | 0 ± 0 (0/10) | 0 ± 0 (0/10) |
Ang II-H (n=12) | 0.17 ± 0.58 (1/12) | 0 ± 0 (0/12) | 0 ± 0 (0/12) | 0 ± 0 (0/12) | 0 ± 0 (0/12) |
Erosions/rupture-associated thrombosis | |||||
Block I | Block II | Block III | Block IV | Block V | |
Vehicle (n=8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) | 0 ± 0 (0/8) |
Ang II-L (n=10) | 1.0 ± 1.25 (5/10) | 0.6 ± 0.52* (6/10) | 0.5 ± 0.972 (3/10) | 0 ± 0 (0/10) | 0 ± 0 (0/10) |
Ang II-H (n=12) | 1.33 ± 1.07** (9/12) | 1.0 ± 1.04* (7/12) | 0.73 ± 0.65* (7/12) | 0 ± 0 (0/12) | 0 ± 0 (0/12) |
The number of each type of lesions was calculated from all sections of each block. The largest number on the section was used to represent each block. The data are expressed as the mean ± SD.
P<0.05
P<0.01 vs vehicle group using the Mann-Whitney U test.
Parentheses indicate the ratio of animals with the lesions to total animal number. Thrombosis includes both partial and occluded thrombi.