Table1.

Examples of commercially available cancer panels

Company	Panel name	Number of genes	Coverage	Note
Life sciences	Ion ampliSeq hotspot cancer panel	50	None indicated	Compatible with FFPE sample
Life sciences	Ion ampliSeq comprehensive cancer panel	409	None indicated	Detect CNV; compatible with FFPE sample
Illumina	TruSight cancer panel	94	20×	Germline only
Illumina	TruSight tumor 15 panel	15	≥500×	Solid tumor somatic variants
Illumina	TruSight amplicon cancer panel	48	~1000×	Somatic mutational hotspots
Illumina	TruSight RNA pan-cancer panel	21,043 exonic region	3 million reads per sample	Gene expression, variant and fusion detection in 1,385 cancer associated genes
IDT	xGen® pan-cancer panel	127	>97% of targeted covered at 30×	Can be expanded by adding custom probes