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. 2016 Mar;13(1):120–135. doi: 10.28092/j.issn.2095-3941.2015.0103

Table1.

Effect of microRNA expression on colorectal cancer treatment

MicroRNA Expression Effect on treatment Reference
* EGFR: Epidermal growth factor receptor. Arrows indicate upregulated or downregulated expression
Let-7 Increased sensitivity to EGFR*-targeted treatment 164-167
MiR-126 Decreased sensitivity to capecitabine and oxaliplatin (XELOX) 168-169
MiR-31 Decreased sensitivity to 5-fluorouracil 170
MiR-192/ miR-215 Increased resistance to 5-fluorouracil 171
MiR-148a Poor sensitivity to oxaliplatin and oxaliplatin plus 5-fluorouracil 172
MiR-21 Poor sensitivity to 5-fluorouracil 173,174
MiR-129 Increased sensitivity to 5-fluorouracil 175
MiR-19b Increased response to 5-fluorouracil 176
MiR-34a Resistance to 5-fluorouracil 177
MiR-143 Increased response to 5-fluorouracil 178
MiR-203 Resistance to oxaliplatin 179