Table3.
LSCC cell line models
Cell Line | Age | Gender | TNM | Stage | Subsite | Type of Lesion | HPV status |
Patient-derived cell lines are from LSCC patients at University of Michigan Comprehensive Cancer Center. Paired cell lines (-10, -17) are derived from subsequent cancers from the same patient. | |||||||
Paired | |||||||
UMSCC-10A | 57 | M | T3N0M0 | III | True cord | Primary | - |
UMSCC-10B | 58 | M | T3N1M0 | III | Lymph node | Metastasis | - |
UMSCC-17A | 47 | F | T1N0M0 | I | Supraglottis | Primary | - |
UMSCC-17B | 47 | F | T1N0M0 | I | Soft tissue | Metastasis | - |
Primary | |||||||
UMSCC-11A | 65 | M | T2N2aM0 | IV | Epiglottis | Primary | - |
UMSCC-23 | 36 | F | T2 N0M0 | II | Supraglottis | Primary | - |
UMSCC-28 | 61 | F | T1 N0M0 | I | True cord | Primary | - |
UMSCC-41 | 78 | M | T2N1M0 | III | Arytenoid | Primary | - |
UMSCC-81B | 53 | M | T2 N0M0 | II | True cord | Primary | - |
UMSCC-105 | 51 | M | T4 N0M0 | IV | True cord | Primary | Positive |
Recurrent and metastatic | |||||||
UMSCC-12 | 71 | M | T2N1M0 | III | Larynx | Recurrence | - |
UMSCC-13 | 60 | M | T3N0M0 | III | Esophagus | Recurrence | - |
UMSCC-25 | 50 | M | T3N0M0 | III | Neck | Metastasis | - |