Fig. 4.

Representative pictures and quantification of staining of β-catenin in Dupuytren’s disease tissue (cord, nodule) as compared to control tissue (unaffected transverse ligaments of the palmar aponeurosis). a photomicrographs. b quantification of staining for β-catenin. * P < 0.05 by Kruskal-Wallis test, followed by post-hoc Dunn’s Multiple Comparisons test. c percentage of nuclear localization measured as colocalization of β-catenin positive signal with hematoxylin signal. * P < 0.05 by Kruskal-Wallis test, followed by post-hoc Dunn’s Multiple Comparisons test. d) Staining for Wnt7b, β-catenin and α-smooth muscle actin (scale bar represents 100 μm) in serial sections of a Dupuytren’s nodule