. Author manuscript; available in PMC: 2016 May 9.

Published in final edited form as: Am J Respir Crit Care Med. 2009 Jan 29;179(7):566–571. doi: 10.1164/rccm.200809-1398OC

Table 3.

Comparison of telomere length in 50 patients with chronic obstructive pulmonary disease and 50 controls matched for sex, age (± 2 years) and smoking history (± 3 pack-years)

	Patients N= 50	Controls N= 50	P value ^*	Adjusted analysis^†
	Patients N= 50	Controls N= 50	P value ^*	OR [95% CI]	P
Male/Female	35/15	35/15	1
Age (years)	59 [49–76]	59 [50–78]	0.69
Pack-years	35 [10–75]	34 [10–72]	0.79
Telomere length T/S ratio	0.58 [0.23–1.18]	0.76 [0.42–1.19]	0.0001	0.00001 [0.8 10⁻⁷–0.002]^#	0.000
≥3^rd tertile (.85), n (%)	2 (4.0)	17 (34.0)		1
]3^rd – 1^st tertile] (.63–.85)	18 (36.0)	16 (32.0)		15.0 [2.8–81.7]	0.002
< 1^st tertile (.63)	30 (60.0)	17 (34.0)	0.000	28.2 [5.0–159.1]	0.000

Data are presented as medians [range] unless stated otherwise.

P value of the non parametric Kruskal-Wallis test or the Fisher exact test as appropriate.

^†

Odds ratios, with 95% confidence intervals estimated by unconditional logistic regression analysis adjusted for age, sex, and number of pack-years.

OR expressed for a change of one unit of measurement after log₁₀ transformation.