TABLE 2 .
Clade-specific SNPs identified between clades C1 and C2
| SNP position in EC958 | SNP in cladea: |
Impactb | Locus tag | Codon | Gene | Product | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| C0 |
C1 | C2 | |||||||||
| C001 | JJ2244 | G213 | CD306 | ||||||||
| 426936 | C | C | C | C | C | T | V→A | EC958_0513 | 295 | sbmA | Peptide antibiotic transporter SbmA |
| 737849 | G | G | G | G | G | A | |||||
| 2838072 | G | G | G | G | G | A | Syn | EC958_2841 | 190 | iscS | Cysteine desulfurase |
| 2878095 | C | C | C | C | C | T | E→G | EC958_2875 | 229 | lepA | GTP-binding elongation factor LepA |
| 3710995 | C | C | C | C | C | T | Syn | EC958_4822 | 302 | acrF | Acriflavine resistance protein F |
| 3905668 | C | C | C | C | C | T | S→P | EC958_3870 | 451 | nikA | Nickel-binding periplasmic protein |
| 4100042 | C | C | C | C | T | C | |||||
| 4397873 | G | G | G | G | A | G | S→N | EC958_4314 | 395 | rmuC | DNA recombination protein RmuC |
a
Boldface indicates clade C1 specific, and italic indicates clade C2 specific.
b
Impact of SNP in bold relative to ST131 clade C2 strain EC958. Syn, synonymous change; non-synonymous changes to protein-coding genes are shown by single letter amino acid codes (EC958 sequence on left, SNP impact on right); blank lines indicate SNP in intergenic region.