TABLE 4.

Levels of immature reducible cross-links (HLNL, DHLNL, and its glycosylation) and mature non-reducible cross-links (Pyr, d-Pyr, and HHMD)

Values represent mean moles/mole of collagen (S.D.) from three independent samples. A, immature cross-links (DHLNL and its glycosylation); B, immature cross-links (HLNL and its glycosylation); C, non-reducible cross-links (Pyr, d-Pyr, and HHMD). *, HHMD was not glycosylated.

^a Total DHLNL = GG-DHLNL + G-DHLNL + non-glycosylated DHLNL.

^b Total HLNL = GG-HLNL + G-HLNL + non-glycosylated HLNL.

^c Significantly different from both WT and Het.

^d ND, not detected.