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ABCA3 gene expression inversely correlates with intracellular miltefosine accumulation. A, intracellular MLF was quantified in L. V. panamensis-infected or uninfected PBMCs-derived macrophages from CL patients (n = 10) exposed ex vivo to MLF for 24 h. B, correlation analysis of intracellular MLF and ABCA3 and ABCB1 gene expression. Statistical correlation was assessed by the Spearman correlation test, and significance was established when p < 0.05.
