FIGURE 5.

Second derivative spectra of mature β₂m fibrils. Second derivative spectra of fibrils by D76N β₂m alone or by an equimolar mixture of WT and D76N β₂m formed after incubation at 37 °C under shear forces and, by WT β₂m at neutral pH in the presence of 20% TFE. Isotopically unlabeled proteins were used. Mean ± S.D. (Error bars) of spectra from 3 independent fibril preparations are shown.