Figure 2.

Switchable partitioning of lipophilic DNA structures on Ld/Lo membrane domains. (A) Oligo DNA/PNA complex colocalized as four-component complexes in the Ld domain, but after cleavage of the complex with restriction endonuclease (EcoR1-HF) the resulting amphipathic components separated from each other. Ratios between the fluorescence intensities in the Lo and Ld phases are given (reproduced with permission from (40), copyright 2012 American Chemical Society). (B) Origami DNA nanorods partition into the Ld phase (marked with DiD), but after addition of Mg²⁺ ions they translocate into the Lo phase, which is fully reversible after removal of the magnesium (with EDTA). Scale bars correspond to 10 μm.