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. 2016 Apr 26;110(8):1698–1707. doi: 10.1016/j.bpj.2016.03.015

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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A variety of membrane-anchored origami DNA nanostructures. (A) Cholesteryl-anchored (orange) origami DNA channel consisting of a barrel-like cap (white) and a transmembrane stem (red), which spontaneously dock to liposomes, as shown on a TEM image (B) (reproduced with permission from (64), copyright 2012 The American Association for the Advancement of Science). (C) Virus-inspired membrane-enveloped DNA nanostructures for biomedical applications; color-enhanced TEM image (D) represents the DNA nanostructure (dark blue) tightly wrapped with unilamellar membrane (light blue) (reproduced with permission from (70) copyright 2014 American Chemical Society). Scale bars 50 nm.