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Central reverse methanogenesis enzymes identified in metagenomic, metatranscriptomic, and metaproteomic analyses.
Green, identified; orange, not addressed; red, not identified. ANME proteins newly detected in seep environments during this study are highlighted in bold text. (McrABG subunits associated with ANME-2c derived fosmids were also detected; no other ANME-2c genes related to reverse methanogenesis were in the metagenomic database.)
