Figure 3.

CCS profiles for [2GA + 2Na]²⁺ ions electrosprayed from 100 nm POPC vesicles plotted as relative abundance versus CCS (Ų). (A and B) Identical data obtained on a Synapt G2 (R ∼25) fit using n = 3 peak fits (A) and n = 4 peak fits (B). (C) High-resolution data obtained on a prototype Bruker TIMS instrument with R > 100. Note the magenta nascent peak revealed under the ADH distribution using n = 4 peak-fits in panel (B) and the high-resolution TIMS instrument. MD simulations were performed previously to generate candidate structures for each population, and the two most populated structures for each conformer are shown at top right. To see this figure in color, go online.